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Cardioprotective effects of Schisantherin A against isoproterenol-induced acute myocardial infarction through amelioration of oxidative stress and inflammation via modulation of PI3K-AKT/Nrf2/ARE and TLR4/MAPK/NF-κB pathways in rats

BACKGROUND AND AIMS: The scientific community is concerned about cardiovascular disease mortality and morbidity, especially myocardial infarction (MI). Schisantherin A (SCA), a dibenzocyclooctadiene lignan monomer found in S. chinensis fruits has cardiovascular advantages such as increasing NO produ...

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Detalles Bibliográficos
Autores principales: Mi, Xiaolong, Zhang, Zhijun, Cheng, Jinfang, Xu, Zheng, Zhu, Kaiyi, Ren, Yunxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401759/
https://www.ncbi.nlm.nih.gov/pubmed/37542250
http://dx.doi.org/10.1186/s12906-023-04081-x