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Decoding the prognostic significance of integrator complex subunit 9 (INTS9) in glioma: links to TP53 mutations, E2F signaling, and inflammatory microenvironments

INTRODUCTION: Gliomas, a type of brain neoplasm, are prevalent and often fatal. Molecular diagnostics have improved understanding, but treatment options are limited. This study investigates the role of INTS9 in processing small nuclear RNA (snRNA), which is crucial to generating mature messenger RNA...

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Detalles Bibliográficos
Autores principales: Lin, Yu-Chieh, Chang, Pei-Chi, Hueng, Dueng-Yuan, Huang, Shih-Ming, Li, Yao-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401760/
https://www.ncbi.nlm.nih.gov/pubmed/37537630
http://dx.doi.org/10.1186/s12935-023-03006-5