Matrix stiffness modulates 3D spheroid sorting and burst-like collective migration

While it is known that cells with differential adhesion tend to segregate and preferentially sort, the physical forces governing sorting and invasion in heterogeneous tumors remain poorly understood. To investigate this, we develop a composite hydrogel that uncouples matrix stiffness and collagen fi...

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Detalles Bibliográficos
Autores principales: Cai, Grace, Li, Xinzhi, Lin, Shan-Shan, Chen, Samuel, Koning, Katherine, Bi, Dapeng, Liu, Allen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401934/
https://www.ncbi.nlm.nih.gov/pubmed/37546827
http://dx.doi.org/10.1101/2023.07.23.549940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401934/
https://www.ncbi.nlm.nih.gov/pubmed/37546827
http://dx.doi.org/10.1101/2023.07.23.549940

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