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Matrix stiffness modulates 3D spheroid sorting and burst-like collective migration
While it is known that cells with differential adhesion tend to segregate and preferentially sort, the physical forces governing sorting and invasion in heterogeneous tumors remain poorly understood. To investigate this, we develop a composite hydrogel that uncouples matrix stiffness and collagen fi...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401934/ https://www.ncbi.nlm.nih.gov/pubmed/37546827 http://dx.doi.org/10.1101/2023.07.23.549940 |