Cargando…
Folding-upon-binding pathways of an intrinsically disordered protein from a deep Markov state model
A central challenge in the study of intrinsically disordered proteins is the characterization of the mechanisms by which they bind their physiological interaction partners. Here, we utilize a deep learning based Markov state modeling approach to characterize the folding-upon-binding pathways observe...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401938/ https://www.ncbi.nlm.nih.gov/pubmed/37546728 http://dx.doi.org/10.1101/2023.07.21.550103 |