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Folding-upon-binding pathways of an intrinsically disordered protein from a deep Markov state model
A central challenge in the study of intrinsically disordered proteins is the characterization of the mechanisms by which they bind their physiological interaction partners. Here, we utilize a deep learning based Markov state modeling approach to characterize the folding-upon-binding pathways observe...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401938/ https://www.ncbi.nlm.nih.gov/pubmed/37546728 http://dx.doi.org/10.1101/2023.07.21.550103 |