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Western diet consumption impairs memory function via dysregulated hippocampus acetylcholine signaling

Western diet (WD) consumption during development yields long-lasting memory impairments, yet the underlying neurobiological mechanisms remain elusive. Here we developed an early life WD rodent model to evaluate whether dysregulated hippocampus (HPC) acetylcholine (ACh) signaling, a pathology associa...

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Detalles Bibliográficos
Autores principales: Hayes, Anna M. R., Lauer, Logan Tierno, Kao, Alicia E., Sun, Shan, Klug, Molly E., Tsan, Linda, Rea, Jessica J., Subramanian, Keshav S., Gu, Cindy, Tanios, Natalie, Ahuja, Arun, Donohue, Kristen N., Décarie-Spain, Léa, Fodor, Anthony A., Kanoski, Scott E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401939/
https://www.ncbi.nlm.nih.gov/pubmed/37546790
http://dx.doi.org/10.1101/2023.07.21.550120