The lncRNA Malat1 Inhibits miR-15/16 to Enhance Cytotoxic T Cell Activation and Memory Cell Formation

Proper activation of cytotoxic T cells via the T cell receptor and the costimulatory receptor CD28 is essential for adaptive immunity against viruses, many intracellular bacteria and cancers. Through biochemical analysis of RNA:protein interactions, we uncovered a non-coding RNA circuit regulating a...

Descripción completa

Detalles Bibliográficos
Autores principales: Wheeler, Benjamin D, Gagnon, John D, Zhu, Wandi S, Muñoz-Sandoval, Priscila, Wong, Simon K, Simeonov, Dimitre R, Li, Zhongmei, Debarge, Rachel, Spitzer, Matthew H, Marson, Alexander, Ansel, K Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401941/
https://www.ncbi.nlm.nih.gov/pubmed/37547023
http://dx.doi.org/10.1101/2023.04.14.536843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401941/
https://www.ncbi.nlm.nih.gov/pubmed/37547023
http://dx.doi.org/10.1101/2023.04.14.536843

Ejemplares similares