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The lncRNA Malat1 Inhibits miR-15/16 to Enhance Cytotoxic T Cell Activation and Memory Cell Formation

Proper activation of cytotoxic T cells via the T cell receptor and the costimulatory receptor CD28 is essential for adaptive immunity against viruses, many intracellular bacteria and cancers. Through biochemical analysis of RNA:protein interactions, we uncovered a non-coding RNA circuit regulating a...

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Detalles Bibliográficos
Autores principales:	Wheeler, Benjamin D, Gagnon, John D, Zhu, Wandi S, Muñoz-Sandoval, Priscila, Wong, Simon K, Simeonov, Dimitre R, Li, Zhongmei, Debarge, Rachel, Spitzer, Matthew H, Marson, Alexander, Ansel, K Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401941/ https://www.ncbi.nlm.nih.gov/pubmed/37547023 http://dx.doi.org/10.1101/2023.04.14.536843

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