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Concurrent profiling of multiscale 3D genome organization and gene expression in single mammalian cells

The organization of mammalian genomes within the nucleus features a complex, multiscale three-dimensional (3D) architecture. The functional significance of these 3D genome features, however, remains largely elusive due to limited single-cell technologies that can concurrently profile genome organiza...

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Detalles Bibliográficos
Autores principales: Zhou, Tianming, Zhang, Ruochi, Jia, Deyong, Doty, Raymond T., Munday, Adam D., Gao, Daniel, Xin, Li, Abkowitz, Janis L., Duan, Zhijun, Ma, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401946/
https://www.ncbi.nlm.nih.gov/pubmed/37546900
http://dx.doi.org/10.1101/2023.07.20.549578