Physicochemical Targeting of Lipid Nanoparticles to the Lungs Induces Clotting: Mechanisms and Solutions

Lipid nanoparticles (LNPs) have become the dominant drug delivery technology in industry, holding the promise to deliver RNA to up- or down-regulate any protein of interest. LNPs have been targeted to specific cell types or organs by physicochemical targeting, in which LNP’s lipid compositions are a...

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Detalles Bibliográficos
Autores principales: Omo-Lamai, Serena, Zamora, Marco E., Patel, Manthan N., Wu, Jichuan, Nong, Jia, Wang, Zhicheng, Peshkova, Alina, Chase, Liam S., Essien, Eno-Obong, Muzykantov, Vladimir, Marcos-Contreras, Oscar, Myerson, Jacob W., Brenner, Jacob S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401951/
https://www.ncbi.nlm.nih.gov/pubmed/37546837
http://dx.doi.org/10.1101/2023.07.21.550080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401951/
https://www.ncbi.nlm.nih.gov/pubmed/37546837
http://dx.doi.org/10.1101/2023.07.21.550080

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