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AlphaFold2 models of the active form of all 437 catalytically competent human protein kinase domains
Humans have 437 catalytically competent protein kinase domains with the typical kinase fold, similar to the structure of Protein Kinase A (PKA). Only 155 of these kinases are in the Protein Data Bank in their active form. The active form of a kinase must satisfy requirements for binding ATP, magnesi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401967/ https://www.ncbi.nlm.nih.gov/pubmed/37547017 http://dx.doi.org/10.1101/2023.07.21.550125 |