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Activation of the Aryl Hydrocarbon Receptor in Endothelial Cells Impairs Ischemic Angiogenesis in Chronic Kidney Disease

RATIONALE: Chronic kidney disease (CKD) is a strong risk factor for peripheral artery disease (PAD) that is associated with worsened clinical outcomes. CKD leads to accumulation of tryptophan metabolites that associate with adverse limb events in PAD and are ligands of the aryl hydrocarbon receptor...

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Detalles Bibliográficos
Autores principales: Palzkill, Victoria R., Tan, Jianna, Yang, Qingping, Morcos, Juliana, Laitano, Orlando, Ryan, Terence E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10401998/
https://www.ncbi.nlm.nih.gov/pubmed/37546909
http://dx.doi.org/10.1101/2023.07.24.550410