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Aub, Vasa and Armi localization to phase separated nuage is dispensable for piRNA biogenesis and transposon silencing in Drosophila

From nematodes to placental mammals, key components of the germline transposon silencing piRNAs pathway localize to phase separated perinuclear granules. In Drosophila, the PIWI protein Aub, DEAD box protein Vasa and helicase Armi localize to nuage granules and are required for ping-pong piRNA ampli...

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Detalles Bibliográficos
Autores principales: Ho, Samantha, Rice, Nicholas P, Yu, Tianxiong, Weng, Zhiping, Theurkauf, William E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402007/
https://www.ncbi.nlm.nih.gov/pubmed/37546958
http://dx.doi.org/10.1101/2023.07.25.549160