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Pre-existing heterogeneity facilitates development of heteroresistance upon gene acquisition
Antibiotic resistance causes 1.27 million global deaths annually and is predicted to worsen. Heteroresistance is a form of resistance in which only a minor and unstable subpopulation of cells of a bacterial isolate are resistant to a given antibiotic, and are therefore often undetected by clinical d...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402025/ https://www.ncbi.nlm.nih.gov/pubmed/37546825 http://dx.doi.org/10.1101/2023.07.24.550411 |