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Pre-existing heterogeneity facilitates development of heteroresistance upon gene acquisition

Antibiotic resistance causes 1.27 million global deaths annually and is predicted to worsen. Heteroresistance is a form of resistance in which only a minor and unstable subpopulation of cells of a bacterial isolate are resistant to a given antibiotic, and are therefore often undetected by clinical d...

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Detalles Bibliográficos
Autores principales: Jaggavarapu, Siddharth, Hufnagel, David A., Weiss, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402025/
https://www.ncbi.nlm.nih.gov/pubmed/37546825
http://dx.doi.org/10.1101/2023.07.24.550411