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RAD54L regulates replication fork progression and nascent strand degradation in BRCA1/2-deficient cells

RAD54L is a DNA motor protein with critical roles in homologous recombination DNA repair (HR). In vitro, RAD54L was also shown to catalyze the reversal and restoration of model replication forks. Little, however, is known about the role of RAD54L in regulating the dynamics of DNA replication in cell...

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Detalles Bibliográficos
Autores principales: Uhrig, Mollie E., Sharma, Neelam, Maxwell, Petey, Selemenakis, Platon, Wiese, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402051/
https://www.ncbi.nlm.nih.gov/pubmed/37546955
http://dx.doi.org/10.1101/2023.07.26.550704