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Predicting Relative Populations of Protein Conformations without a Physics Engine Using AlphaFold2

This paper presents a novel approach for predicting the relative populations of protein conformations using AlphaFold 2, an AI-powered method that has revolutionized biology by enabling the accurate prediction of protein structures. While AlphaFold 2 has shown exceptional accuracy and speed, it is d...

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Detalles Bibliográficos
Autores principales: da Silva, Gabriel Monteiro, Cui, Jennifer Y., Dalgarno, David C., Lisi, George P., Rubenstein, Brenda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402055/
https://www.ncbi.nlm.nih.gov/pubmed/37546747
http://dx.doi.org/10.1101/2023.07.25.550545