The microbial metabolite Urolithin A reduces C. difficile toxin expression and repairs toxin-induced epithelial damage

Clostridioides difficile is a gram-positive, anaerobic, spore-forming bacterium that is responsible for antibiotic-associated pseudomembranous colitis. Clostridioides difficile infection (CDI) symptoms can range from diarrhea to life-threatening colon damage. Toxins produced by C. difficile (TcdA an...

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Detalles Bibliográficos
Autores principales: Ghosh, Sweta, Erickson, Daniel, Chua, Michelle J, Collins, James, Jala, Venkatakrishna Rao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402075/
https://www.ncbi.nlm.nih.gov/pubmed/37546803
http://dx.doi.org/10.1101/2023.07.24.550342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402075/
https://www.ncbi.nlm.nih.gov/pubmed/37546803
http://dx.doi.org/10.1101/2023.07.24.550342

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