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The microbial metabolite Urolithin A reduces C. difficile toxin expression and repairs toxin-induced epithelial damage
Clostridioides difficile is a gram-positive, anaerobic, spore-forming bacterium that is responsible for antibiotic-associated pseudomembranous colitis. Clostridioides difficile infection (CDI) symptoms can range from diarrhea to life-threatening colon damage. Toxins produced by C. difficile (TcdA an...
Autores principales: | Ghosh, Sweta, Erickson, Daniel, Chua, Michelle J, Collins, James, Jala, Venkatakrishna Rao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402075/ https://www.ncbi.nlm.nih.gov/pubmed/37546803 http://dx.doi.org/10.1101/2023.07.24.550342 |
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