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Novel centriolar defects underlie a primary ciliary dyskinesia phenotype in an adenylate kinase 7 deficient ciliated epithelium

The skin of Xenopus embryos contains numerous multiciliated cells (MCCs), which collectively generate a directed fluid flow across the epithelial surface essential for distributing the overlaying mucous. MCCs develop into highly specialized cells to generate this flow, containing approximately 150 e...

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Detalles Bibliográficos
Autores principales: Sheridan, Jennifer, Grata, Aline, Suva, Eve E., Bresteau, Enzo, Mitchell, Linus R., Hassan, Osama, Mitchell, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402086/
https://www.ncbi.nlm.nih.gov/pubmed/37546962
http://dx.doi.org/10.1101/2023.07.25.550535