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Signaling specificity and kinetics of the human metabotropic glutamate receptors.
Metabotropic glutamate receptors (mGluRs) are obligate dimer G protein coupled receptors that can all function as homodimers. Here, each mGluR homodimer was examined for its G protein coupling profile using a BRET based assay that detects the interaction between a split YFP-tagged Gβ(1)γ(2) and a Na...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402105/ https://www.ncbi.nlm.nih.gov/pubmed/37546908 http://dx.doi.org/10.1101/2023.07.24.550373 |