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Downregulation of lysosomal trafficking in ARPE19 cells leads to decreased transfection efficiency at high passage

PURPOSE: ARPE19 cells are a commonly used cell culture model for the study of retinal pigment epithelial cell biology and pathologies. However, numerous studies have demonstrated that ARPE19 undergo morphologic, transcriptomic and genomic alterations over time and with increasing passage number. Her...

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Detalles Bibliográficos
Autores principales: Hood, Erika M.S., Lipinski, Rachel A. Jones, Lipinski, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402107/
https://www.ncbi.nlm.nih.gov/pubmed/37546846
http://dx.doi.org/10.1101/2023.07.26.550695