Inducible nitric oxide synthase (iNOS) is necessary for GBP-mediated T. gondii restriction in murine macrophages via vacuole nitration and intravacuolar network collapse

Toxoplasma gondii is an obligate intracellular, protozoan pathogen of rodents and humans. T. gondii’s ability to grow within cells and evade cell-autonomous immunity depends on the integrity of the parasitophorous vacuole (PV). Interferon-inducible guanylate binding proteins (GBPs) are central media...

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Detalles Bibliográficos
Autores principales: Zhao, Xiao-Yu, Lempke, Samantha L., Urbán Arroyo, Jan C., Yin, Bocheng, Holness, Nadia K., Smiley, Jamison, Ewald, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402109/
https://www.ncbi.nlm.nih.gov/pubmed/37546987
http://dx.doi.org/10.1101/2023.07.24.549965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402109/
https://www.ncbi.nlm.nih.gov/pubmed/37546987
http://dx.doi.org/10.1101/2023.07.24.549965

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