Enhanced microglial dynamics and paucity of tau seeding in the amyloid plaque microenvironment contributes to cognitive resilience in Alzheimer’s disease

Asymptomatic Alzheimer’s disease (AsymAD) describes the status of subjects with preserved cognition but with identifiable Alzheimer’s disease (AD) brain pathology (i.e. Aβ-amyloid deposits, neuritic plaques, and neurofibrillary tangles) at autopsy. In this study, we investigated the postmortem brain...

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Detalles Bibliográficos
Autores principales: Jury-Garfe, Nur, You, Yanwen, Martínez, Pablo, Redding-Ochoa, Javier, Karahan, Hande, Johnson, Travis S., Zhang, Jie, Kim, Jungsu, Troncoso, Juan C., Lasagna-Reeves, Cristian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402121/
https://www.ncbi.nlm.nih.gov/pubmed/37546928
http://dx.doi.org/10.1101/2023.07.27.550884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402121/
https://www.ncbi.nlm.nih.gov/pubmed/37546928
http://dx.doi.org/10.1101/2023.07.27.550884

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