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Enhanced microglial dynamics and paucity of tau seeding in the amyloid plaque microenvironment contributes to cognitive resilience in Alzheimer’s disease
Asymptomatic Alzheimer’s disease (AsymAD) describes the status of subjects with preserved cognition but with identifiable Alzheimer’s disease (AD) brain pathology (i.e. Aβ-amyloid deposits, neuritic plaques, and neurofibrillary tangles) at autopsy. In this study, we investigated the postmortem brain...
Autores principales: | Jury-Garfe, Nur, You, Yanwen, Martínez, Pablo, Redding-Ochoa, Javier, Karahan, Hande, Johnson, Travis S., Zhang, Jie, Kim, Jungsu, Troncoso, Juan C., Lasagna-Reeves, Cristian A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402121/ https://www.ncbi.nlm.nih.gov/pubmed/37546928 http://dx.doi.org/10.1101/2023.07.27.550884 |
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