Heparan sulfate promotes TRAIL-induced tumor cell apoptosis

TRAIL (TNF-related apoptosis-inducing ligand) is a potent inducer of tumor cell apoptosis through TRAIL receptors. While it has been previously pursued as a potential anti-tumor therapy, the enthusiasm subsided due to unsuccessful clinical trials and the fact that many tumors are resistant to TRAIL....

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Detalles Bibliográficos
Autores principales: Luo, Yin, Hao, Huanmeng, Wang, Zhangjie, Ong, Chihyean, Dutcher, Robert, Xu, Yongmei, Liu, Jian, Pedersen, Lars C., Xu, Ding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402122/
https://www.ncbi.nlm.nih.gov/pubmed/37546770
http://dx.doi.org/10.1101/2023.07.26.550758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402122/
https://www.ncbi.nlm.nih.gov/pubmed/37546770
http://dx.doi.org/10.1101/2023.07.26.550758

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