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Interaction of high-fat diet and brain trauma alters adipose tissue macrophages and brain microglia associated with exacerbated cognitive dysfunction

Obesity increases the morbidity and mortality of traumatic brain injury (TBI). We performed a detailed analysis of transcriptomic changes in the brain and adipose tissue to examine the interactive effects between high-fat diet-induced obesity (DIO) and TBI in relation to central and peripheral infla...

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Detalles Bibliográficos
Autores principales: Henry, Rebecca J., Barrett, James P., Vaida, Maria, Khan, Niaz Z., Makarevich, Oleg, Ritzel, Rodney M., Faden, Alan I., Stoica, Bogdan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402152/
https://www.ncbi.nlm.nih.gov/pubmed/37546932
http://dx.doi.org/10.1101/2023.07.28.550986