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Multiscale modelling of chromatin 4D organization in SARS-CoV-2 infected cells

SARS-CoV-2 is able to re-structure chromatin organization and alters the epigenomic landscape of the host genome, though the mechanisms that produce such changes are still poorly understood. Here, we investigate with polymer physics chromatin re-organization of the host genome, in space and time upo...

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Detalles Bibliográficos
Autores principales: Chiariello, Andrea M., Abraham, Alex, Bianco, Simona, Esposito, Andrea, Vercellone, Francesca, Conte, Mattia, Fontana, Andrea, Nicodemi, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402158/
https://www.ncbi.nlm.nih.gov/pubmed/37546924
http://dx.doi.org/10.1101/2023.07.27.550709