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Splam: a deep-learning-based splice site predictor that improves spliced alignments

The process of splicing messenger RNA to remove introns plays a central role in creating genes and gene variants. Here we describe Splam, a novel method for predicting splice junctions in DNA based on deep residual convolutional neural networks. Unlike some previous models, Splam looks at a relative...

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Detalles Bibliográficos
Autores principales: Chao, Kuan-Hao, Mao, Alan, Salzberg, Steven L, Pertea, Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402160/
https://www.ncbi.nlm.nih.gov/pubmed/37546880
http://dx.doi.org/10.1101/2023.07.27.550754