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Splam: a deep-learning-based splice site predictor that improves spliced alignments
The process of splicing messenger RNA to remove introns plays a central role in creating genes and gene variants. Here we describe Splam, a novel method for predicting splice junctions in DNA based on deep residual convolutional neural networks. Unlike some previous models, Splam looks at a relative...
Autores principales: | Chao, Kuan-Hao, Mao, Alan, Salzberg, Steven L, Pertea, Mihaela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402160/ https://www.ncbi.nlm.nih.gov/pubmed/37546880 http://dx.doi.org/10.1101/2023.07.27.550754 |
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