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Genetic context drives age-related disparities in synaptic maintenance and structure across cortical and hippocampal neuronal circuits
The disconnection of neuronal circuits through synaptic loss is presumed to be a major driver of age-related cognitive decline. Age-related cognitive decline is heterogeneous, yet whether genetic mechanisms differentiate successful from unsuccessful cognitive decline through synaptic structural mech...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402174/ https://www.ncbi.nlm.nih.gov/pubmed/37546799 http://dx.doi.org/10.1101/2023.07.27.550869 |