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Local Disordered Region Sampling (LDRS) for Ensemble Modeling of Proteins with Experimentally Undetermined or Low Confidence Prediction Segments

The Local Disordered Region Sampling (LDRS, pronounced loaders) tool, developed for the IDPConformerGenerator platform (Teixeira et al. 2022), provides a method for generating all-atom conformations of intrinsically disordered regions (IDRs) at N- and C-termini of and in loops or linkers between fol...

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Detalles Bibliográficos
Autores principales: Liu, Zi Hao, Teixeira, João M.C., Zhang, Oufan, Tsangaris, Thomas E., Li, Jie, Gradinaru, Claudiu C., Head-Gordon, Teresa, Forman-Kay, Julie D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402175/
https://www.ncbi.nlm.nih.gov/pubmed/37546943
http://dx.doi.org/10.1101/2023.07.25.550520