Deciphering the genetic architecture of atrial fibrillation offers insights into disease prediction, pathophysiology and downstream sequelae

AIMS: The study aimed to discover novel genetic loci for atrial fibrillation (AF), explore the shared genetic etiologies between AF and other cardiovascular and cardiometabolic traits, and uncover AF pathogenesis using Mendelian randomization analysis. METHODS AND RESULTS: We conducted a genome-wide...

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Detalles Bibliográficos
Autores principales: Yuan, Shuai, Li, Yuying, Wang, Lijuan, Xu, Fengzhe, Chen, Jie, Levin, Michael G, Xiong, Ying, Voight, Benjamin F., Damrauer, Scott M, Gill, Dipender, Burgess, Stephen, Åkesson, Agneta, Michaëlsson, Karl, Li, Xue, Shen, Xia, Larsson, Susanna C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402218/
https://www.ncbi.nlm.nih.gov/pubmed/37546828
http://dx.doi.org/10.1101/2023.07.20.23292938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402218/
https://www.ncbi.nlm.nih.gov/pubmed/37546828
http://dx.doi.org/10.1101/2023.07.20.23292938

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