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Leukocytes carrying Clonal Hematopoiesis of Indeterminate Potential (CHIP) Mutations invade Human Atherosclerotic Plaques

BACKGROUND: Leukocyte progenitors derived from clonal hematopoiesis of undetermined potential (CHIP) are associated with increased cardiovascular events. However, the prevalence and functional relevance of CHIP in coronary artery disease (CAD) are unclear, and cells affected by CHIP have not been de...

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Detalles Bibliográficos
Autores principales: von Scheidt, Moritz, Bauer, Sabine, Ma, Angela, Hao, Ke, Kessler, Thorsten, Vilne, Baiba, Wang, Ying, Hodonsky, Chani J., Ghosh, Saikat K.B., Mokry, Michal, Gao, Hua, Kawai, Kenji, Sakamoto, Atsushi, Kaiser, Juliane, Bongiovanni, Dario, Fleig, Julia, Oldenbuettel, Lilith, Chen, Zhifen, Moggio, Aldo, Sager, Hendrik B., Hecker, Judith S., Bassermann, Florian, Maegdefessel, Lars, Miller, Clint L., Koenig, Wolfgang, Zeiher, Andreas M., Dimmeler, Stefanie, Graw, Matthias, Braun, Christian, Ruusalepp, Arno, Leeper, Nicholas J., Kovacic, Jason C., Björkegren, Johan L.M., Schunkert, Heribert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402238/
https://www.ncbi.nlm.nih.gov/pubmed/37546840
http://dx.doi.org/10.1101/2023.07.22.23292754