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Assessing and harnessing updated polyketide synthase modules through combinatorial engineering

The modular nature of polyketide assembly lines and the significance of their products make them prime targets for combinatorial engineering. While short synthases constructed using the recently updated module boundary have been shown to outperform those using the traditional boundary, larger syntha...

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Detalles Bibliográficos
Autores principales: Ray, Katherine A., Lutgens, Joshua D., Bista, Ramesh, Zhang, Jie, Desai, Ronak R., Hirsch, Melissa, Miyazawa, Takeshi, Cordova, Antonio, Keatinge-Clay, Adrian T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402262/
https://www.ncbi.nlm.nih.gov/pubmed/37546965
http://dx.doi.org/10.21203/rs.3.rs-3157617/v1