Spatially resolved metabolomics and isotope tracing reveal dynamic metabolic responses of dentate granule neurons with acute stimulation

Neuronal activity creates an intense energy demand that must be met by rapid metabolic responses. To investigate metabolic adaptations in the neuron-enriched dentate granule cell (DGC) layer within its native tissue environment, we employed murine acute hippocampal brain slices coupled with fast met...

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Detalles Bibliográficos
Autores principales: Miller, Anne, York, Elisa, Stopka, Sylwia, Martínez-François, Juan, Hossain, Md Amin, Baquer, Gerard, Regan, Michael, Agar, Nathalie, Yellen, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402263/
https://www.ncbi.nlm.nih.gov/pubmed/37546759
http://dx.doi.org/10.21203/rs.3.rs-2276903/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402263/
https://www.ncbi.nlm.nih.gov/pubmed/37546759
http://dx.doi.org/10.21203/rs.3.rs-2276903/v1

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