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Spatially resolved metabolomics and isotope tracing reveal dynamic metabolic responses of dentate granule neurons with acute stimulation
Neuronal activity creates an intense energy demand that must be met by rapid metabolic responses. To investigate metabolic adaptations in the neuron-enriched dentate granule cell (DGC) layer within its native tissue environment, we employed murine acute hippocampal brain slices coupled with fast met...
Autores principales: | Miller, Anne, York, Elisa, Stopka, Sylwia, Martínez-François, Juan, Hossain, Md Amin, Baquer, Gerard, Regan, Michael, Agar, Nathalie, Yellen, Gary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402263/ https://www.ncbi.nlm.nih.gov/pubmed/37546759 http://dx.doi.org/10.21203/rs.3.rs-2276903/v1 |
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