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Notch Intracellular Domains form Transcriptionally Active Heterodimeric Complexes on Sequence-paired Sites
Notch signaling is universally conserved in metazoans where it is important for a wide variety of both normal and abnormal physiology. All four mammalian Notch receptors are activated by a conserved mechanism that releases Notch intracellular domains (NICDs) from the plasma membrane to translocate t...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Journal Experts
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402268/ https://www.ncbi.nlm.nih.gov/pubmed/37546896 http://dx.doi.org/10.21203/rs.3.rs-3147210/v1 |