Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A.Z by SWR1C

The SWR1C chromatin remodeling enzyme catalyzes the ATP-dependent exchange of nucleosomal histone H2A for the histone variant H2A.Z, a key variant involved in a multitude of nuclear functions. How the 14-subunit SWR1C engages the nucleosomal substrate remains largely unknown. Numerous studies on the...

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Detalles Bibliográficos
Autores principales: Baier, Alexander S., Gioacchini, Nathan, Eek, Priit, Tan, Song, Peterson, Craig L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402270/
https://www.ncbi.nlm.nih.gov/pubmed/37546845
http://dx.doi.org/10.21203/rs.3.rs-3050911/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402270/
https://www.ncbi.nlm.nih.gov/pubmed/37546845
http://dx.doi.org/10.21203/rs.3.rs-3050911/v1

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