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Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A.Z by SWR1C
The SWR1C chromatin remodeling enzyme catalyzes the ATP-dependent exchange of nucleosomal histone H2A for the histone variant H2A.Z, a key variant involved in a multitude of nuclear functions. How the 14-subunit SWR1C engages the nucleosomal substrate remains largely unknown. Numerous studies on the...
Autores principales: | Baier, Alexander S., Gioacchini, Nathan, Eek, Priit, Tan, Song, Peterson, Craig L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402270/ https://www.ncbi.nlm.nih.gov/pubmed/37546845 http://dx.doi.org/10.21203/rs.3.rs-3050911/v1 |
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