BSBM-20 INVESTIGATING THE ROLE OF OXIDATIVE PHOSPHORYLATION (OXPHOS) IN CD4+ T CELL ACTIVATION AND RESPONSE TO ANTI-PD1/ANTI-LAG3 IMMUNOTHERAPY IN MELANOMA BRAIN METASTASIS (MBM)

Brain metastasis is a frequent and deadly complication of metastatic melanoma. While extracranial metastases (ECMs) are often treatable, MBMs remain a critical treatment (tx) challenge to overcome. We previously showed that MBMs are characterized by increased utilization of OXPHOS compared to ECMs,...

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Detalles Bibliográficos
Autores principales: Guerrieri, Renato, Cortez, Jacob, Liu, Alice, Jeong, Kate-Yeonjae, Knighton, Barbara, Ferguson, Sherise, Davies, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Basic Science of Brain Metastases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402296/
http://dx.doi.org/10.1093/noajnl/vdad070.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402296/
http://dx.doi.org/10.1093/noajnl/vdad070.016

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