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BSBM-22 CHARACTERIZATION OF CIRCULATORY SHEAR STRESS-INDUCED MOLECULAR CHANGES IN LUNG ADENOCARCINOMA CELLS AND IMPLICATIONS IN BRAIN METASTASIS

INTRODUCTION: Lung cancer is the most common tumor to metastasize to the brain, as 40% of patients develop brain metastasis (BM). Once diagnosed, survival is only 6.5-10 months. A potential target to prevent BM is circulating tumor cells (CTCs). The mechanisms that mediate a CTCs adaptation to the h...

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Detalles Bibliográficos
Autores principales: Marenco-Hillembrand, Lina, McKevitt, Chase, Bamimore, Michael, Wickland, Daniel, Schiapparelli, Paula, Maharjan, Sushila, Zhang, Yu Shrike, Quinones-Hinojosa, Alfredo, Chaichana, Kaisorn L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402317/
http://dx.doi.org/10.1093/noajnl/vdad070.018