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TIPS-08 ACTION: A RANDOMIZED PHASE 3 STUDY OF DORDAVIPRONE (ONC201) IN PATIENTS WITH NEWLY DIAGNOSED H3 K27M-MUTANT DIFFUSE GLIOMA

BACKGROUND: H3 K27M-mutant diffuse midline glioma is a universally fatal malignancy primarily affecting children and young adults. While radiotherapy (RT) provides transient benefit, no effective systemic therapy is currently available and current standard of care is RT followed by monitoring. Dorda...

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Detalles Bibliográficos
Autores principales: Arrillaga-Romany, Isabel, Lassman, Andrew, McGovern, Susan, Mueller, Sabine, Nabors, Louis Burt, van den Bent, Martin, Vogelbaum, Michael, Allen, Joshua E, Melemed, Allen S, Tarapore, Rohinton, Wen, Patrick, Cloughsey, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402351/
http://dx.doi.org/10.1093/noajnl/vdad070.139