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TIPS-08 ACTION: A RANDOMIZED PHASE 3 STUDY OF DORDAVIPRONE (ONC201) IN PATIENTS WITH NEWLY DIAGNOSED H3 K27M-MUTANT DIFFUSE GLIOMA
BACKGROUND: H3 K27M-mutant diffuse midline glioma is a universally fatal malignancy primarily affecting children and young adults. While radiotherapy (RT) provides transient benefit, no effective systemic therapy is currently available and current standard of care is RT followed by monitoring. Dorda...
Autores principales: | Arrillaga-Romany, Isabel, Lassman, Andrew, McGovern, Susan, Mueller, Sabine, Nabors, Louis Burt, van den Bent, Martin, Vogelbaum, Michael, Allen, Joshua E, Melemed, Allen S, Tarapore, Rohinton, Wen, Patrick, Cloughsey, Timothy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402351/ http://dx.doi.org/10.1093/noajnl/vdad070.139 |
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