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BSBM-03 A NOVEL COMBINED IMMUNOTHERAPY TO IMPROVE THERAPEUTIC RESPONSES IN SYMPTOMATIC BRAIN METASTASIS BASED ON TARGETING A SUBPOPULATION OF IMMUNOSUPPRESSIVE ASTROCYTES

The diagnosis of brain metastasis involves high morbidity and mortality. Recently, immune checkpoint blockade antibodies (ICB) have shown clinical benefits mainly when applied to asymptomatic brain metastasis patients. However, variability is broad and responses to this therapy drop considerably whe...

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Detalles Bibliográficos
Autores principales: Priego, Neibla, de Pablos-Aragoneses, Ana, Perea-García, María, Álvaro-Espinosa, Laura, Hernández-Oliver, Carolina, Martínez-Saez, Elena, Pérez-Núñez, Ángel, Hernández-Laín, Aurelio, Sanz-Pamplona, Rebeca, Schmitz, Marc, Crocker, Stephen J, Serrano, Diego, Calvo, Alfonso, Palazón, Asís, Valiente, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402391/
http://dx.doi.org/10.1093/noajnl/vdad070.001