SYST-26 INVESTIGATING THE FUNCTIONAL ROLE OF GPNMB IN GLIOBLASTOMA AND THE TUMOR IMMUNE MICROENVIRONMENT AND ITS TARGETED ELIMINATION USING CAR-T CELLS

INTRODUCTION: Glycoprotein nonmetastatic melanoma protein B (GPNMB) is active in the extracellular matrix of glioblastoma and presents a promising immunotherapy target for both tumor cells and immunosuppressive macrophages. METHODS: Immunohistochemistry was performed on patient derived xenograft (PD...

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Detalles Bibliográficos
Autores principales: Savage, Neil, Zemp, Franz, Mikolajewicz, Nicholas, Han, Hong, Venugopal, Chitra, Tatari, Nazanin, Chokshi, Chirayu, Kislinger, Thomas, Mahoney, Douglas, Moffat, Jason, Singh, Sheila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Systemic Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402432/
http://dx.doi.org/10.1093/noajnl/vdad070.128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402432/
http://dx.doi.org/10.1093/noajnl/vdad070.128

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