BSBM-16 HLA CLASS-I ANTIGEN PRESENTATION MACHINERY AND IFN-γ PATHWAY ALTERATIONS IN LUNG CANCER BRAIN METASTASES

BACKGROUND: Immune checkpoint inhibitors (ICI) can have activity in lung cancer brain metastases (LBM). However, the duration of responses is limited and most patients with LBM do not benefit from these therapies. Alterations in HLA class-I antigen presentation machinery via beta-2 microglobulin (B2...

Descripción completa

Detalles Bibliográficos
Autores principales: Vilarino, Noelia, de Rodas, Miguel Lopez, Lu, Benjamin Y, Goldberg, Sarah, Schalper, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Basic Science of Brain Metastases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402438/
http://dx.doi.org/10.1093/noajnl/vdad070.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402438/
http://dx.doi.org/10.1093/noajnl/vdad070.012

Ejemplares similares