BSBM-18 SINGLE-CELL PROFILING TUMOR-INFILTRATING IMMUNE CELLS REVEALS CXCL13(+) FOLLICULAR HELPER-LIKE CD4(+) T CELLS IN HUMAN BRAIN TUMORS

While therapies enhancing antitumor T cell function have clinical efficacy for patients with brain metastases, patients with high-grade gliomas fail to benefit. How the brain tumor microenvironment differentially shapes T cell function remains unknown. We performed droplet-based single-cell RNA and...

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Detalles Bibliográficos
Autores principales: Lu, Benjamin, Lucca, Liliana, DiStasio, Marcello, Liu, Yang, Pham, Giang, Buitrago-Pocasangre, Nicholas, Arnal-Estape, Anna, Moliterno, Jennifer, Chiang, Veronica, Omuro, Antonio, Hafler, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Basic Science of Brain Metastases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402449/
http://dx.doi.org/10.1093/noajnl/vdad070.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402449/
http://dx.doi.org/10.1093/noajnl/vdad070.014

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