Reframing the link between metabolism and NLRP3 inflammasome: therapeutic opportunities

Inflammasomes are multiprotein signaling platforms in the cytosol that senses exogenous and endogenous danger signals and respond with the maturation and secretion of IL-1β and IL-18 and pyroptosis to induce inflammation and protect the host. The inflammasome best studied is the Nucleotide-binding o...

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Detalles Bibliográficos
Autores principales: Ortega, Miguel A., De Leon-Oliva, Diego, García-Montero, Cielo, Fraile-Martinez, Oscar, Boaru, Diego Liviu, de Castro, Amador Velazquez, Saez, Miguel A., Lopez-Gonzalez, Laura, Bujan, Julia, Alvarez-Mon, Miguel Angel, García-Honduvilla, Natalio, Diaz-Pedrero, Raul, Alvarez-Mon, Melchor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402745/
https://www.ncbi.nlm.nih.gov/pubmed/37545507
http://dx.doi.org/10.3389/fimmu.2023.1232629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402745/
https://www.ncbi.nlm.nih.gov/pubmed/37545507
http://dx.doi.org/10.3389/fimmu.2023.1232629

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