Cargando…

Reframing the link between metabolism and NLRP3 inflammasome: therapeutic opportunities

Inflammasomes are multiprotein signaling platforms in the cytosol that senses exogenous and endogenous danger signals and respond with the maturation and secretion of IL-1β and IL-18 and pyroptosis to induce inflammation and protect the host. The inflammasome best studied is the Nucleotide-binding o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ortega, Miguel A., De Leon-Oliva, Diego, García-Montero, Cielo, Fraile-Martinez, Oscar, Boaru, Diego Liviu, de Castro, Amador Velazquez, Saez, Miguel A., Lopez-Gonzalez, Laura, Bujan, Julia, Alvarez-Mon, Miguel Angel, García-Honduvilla, Natalio, Diaz-Pedrero, Raul, Alvarez-Mon, Melchor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10402745/ https://www.ncbi.nlm.nih.gov/pubmed/37545507 http://dx.doi.org/10.3389/fimmu.2023.1232629

Ejemplares similares

Understanding HAT1: A Comprehensive Review of Noncanonical Roles and Connection with Disease
por: Ortega, Miguel A., et al.
Publicado: (2023)

Unraveling the New Perspectives on Antimicrobial Hydrogels: State-of-the-Art and Translational Applications
por: Ortega, Miguel A., et al.
Publicado: (2023)

Exploring the Role of Mediterranean and Westernized Diets and Their Main Nutrients in the Modulation of Oxidative Stress in the Placenta: A Narrative Review
por: García-Montero, Cielo, et al.
Publicado: (2023)

Placentas from Women with Late-Onset Preeclampsia Exhibit Increased Expression of the NLRP3 Inflammasome Machinery
por: Garcia-Puente, Luis M., et al.
Publicado: (2023)

AIF1: Function and Connection with Inflammatory Diseases
por: De Leon-Oliva, Diego, et al.
Publicado: (2023)

A General Overview on the Hyperbaric Oxygen Therapy: Applications, Mechanisms and Translational Opportunities
por: Ortega, Miguel A., et al.
Publicado: (2021)

Advanced Hydrogel-Based Strategies for Enhanced Bone and Cartilage Regeneration: A Comprehensive Review
por: De Leon-Oliva, Diego, et al.
Publicado: (2023)

The Pivotal Role of the Placenta in Normal and Pathological Pregnancies: A Focus on Preeclampsia, Fetal Growth Restriction, and Maternal Chronic Venous Disease
por: Ortega, Miguel A., et al.
Publicado: (2022)

Assessment of Tissue Expression of the Oxytocin–Vasopressin Pathway in the Placenta of Women with a First-Episode Psychosis during Pregnancy
por: Ortega, Miguel A., et al.
Publicado: (2023)

Oxidative Stress Markers Are Associated with a Poor Prognosis in Patients with Pancreatic Cancer
por: Ortega, Miguel A., et al.
Publicado: (2022)

Contribution of the Elastic Component and Venous Wall Arterialization in Patients with Venous Reflux
por: Ortega, Miguel A., et al.
Publicado: (2022)

Overexpression of glycolysis markers in placental tissue of pregnant women with chronic venous disease: a histological study
por: Ortega, Miguel A, et al.
Publicado: (2022)

Newborns of Mothers with Venous Disease during Pregnancy Show Increased Levels of Lipid Peroxidation and Markers of Oxidative Stress and Hypoxia in the Umbilical Cord
por: Ortega, Miguel A., et al.
Publicado: (2021)

Modification of the Polymer of a Bone Cement with Biodegradable Microspheres of PLGA and Loading with Daptomycin and Vancomycin Improve the Response to Bone Tissue Infection
por: García-García, Joaquin, et al.
Publicado: (2022)

Understanding Chronic Venous Disease: A Critical Overview of Its Pathophysiology and Medical Management
por: Ortega, Miguel A., et al.
Publicado: (2021)

Towards an updated view on the clinical management of pancreatic adenocarcinoma: Current and future perspectives
por: Pekarek, Leonel, et al.
Publicado: (2021)

Implication of ERBB2 as a Predictive Tool for Survival in Patients with Pancreatic Cancer in Histological Studies
por: Ortega, Miguel A., et al.
Publicado: (2022)

An integrative look at SARS-CoV-2 (Review)
por: Ortega, Miguel A., et al.
Publicado: (2021)

Tissue remodelling and increased DNA damage in patients with incompetent valves in chronic venous insufficiency
por: Ortega, Miguel A., et al.
Publicado: (2021)

Update on uveal melanoma: Translational research from biology to clinical practice (Review)
por: Ortega, Miguel A., et al.
Publicado: (2020)

Applications of Polymeric Composites in Bone Tissue Engineering and Jawbone Regeneration
por: Fraile-Martínez, Oscar, et al.
Publicado: (2021)

Physical Activity as an Imperative Support in Breast Cancer Management
por: Ortega, Miguel A., et al.
Publicado: (2020)

Increased Expression of Tetraspanins, ALIX and HSP-70 in the Placenta Tissue of Women with Chronic Venous Disease during Pregnancy
por: Ortega, Miguel A, et al.
Publicado: (2023)

Clinical and Novel Biomarkers in Penile Carcinoma: A Prospective Review
por: Pekarek, Leonel, et al.
Publicado: (2022)

Considering the Effects and Maternofoetal Implications of Vascular Disorders and the Umbilical Cord
por: Sánchez-Trujillo, Lara, et al.
Publicado: (2022)

Venous Wall of Patients with Chronic Venous Disease Exhibits a Glycolytic Phenotype
por: Fraile-Martinez, Oscar, et al.
Publicado: (2022)

Patients with Invasive Lobular Carcinoma Show a Significant Increase in IRS-4 Expression Compared to Infiltrative Ductal Carcinoma—A Histopathological Study
por: Ortega, Miguel A., et al.
Publicado: (2022)

Histopathological study of JNK in venous wall of patients with chronic venous insufficiency related to osteogenesis process
por: Ortega, Miguel A, et al.
Publicado: (2021)

Clinical Applications of Classical and Novel Biological Markers of Pancreatic Cancer
por: Pekarek, Leonel, et al.
Publicado: (2022)

Chronic Venous Disease during Pregnancy Is Related to Inflammation of the Umbilical Cord: Role of Allograft Inflammatory Factor 1 (AIF-1) and Interleukins 10 (IL-10), IL-12 and IL-18
por: Sánchez-Trujillo, Lara, et al.
Publicado: (2023)

An increase in elastogenic components in the placental villi of women with chronic venous disease during pregnancy is associated with decreased EGFL7 expression level
por: Ortega, Miguel A., et al.
Publicado: (2021)

Chronic venous disease patients show increased IRS-4 expression in the great saphenous vein wall
por: Ortega, Miguel A, et al.
Publicado: (2021)

High Sensitivity of Human Adipose Stem Cells to Differentiate into Myofibroblasts in the Presence of C. aspersa Egg Extract
por: García-Honduvilla, Natalio, et al.
Publicado: (2017)

Increased Angiogenesis and Lymphangiogenesis in the Placental Villi of Women with Chronic Venous Disease during Pregnancy
por: Ortega, Miguel A, et al.
Publicado: (2020)

Type 2 Diabetes Mellitus Associated with Obesity (Diabesity). The Central Role of Gut Microbiota and Its Translational Applications
por: Ortega, Miguel A., et al.
Publicado: (2020)

An Updated Review of SARS-CoV-2 Vaccines and the Importance of Effective Vaccination Programs in Pandemic Times
por: García-Montero, Cielo, et al.
Publicado: (2021)

Chronic Venous Disease in Pregnant Women Causes an Increase in ILK in the Placental Villi Associated with a Decrease in E-Cadherin
por: Ortega, Miguel A., et al.
Publicado: (2022)

Is Insulin Receptor Substrate4 (IRS4) a Platform Involved in the Activation of Several Oncogenes?
por: Guijarro, Luis G., et al.
Publicado: (2023)

Clinical and Translational Applications of Serological and Histopathological Biomarkers in Metastatic Breast Cancer: A Comprehensive Review
por: Pekarek, Leonel, et al.
Publicado: (2023)

Upregulation of VEGF and PEDF in Placentas of Women with Lower Extremity Venous Insufficiency during Pregnancy and Its Implication in Villous Calcification
por: Ortega, Miguel A, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_3lfkoqj446qgga17a01lv3t88e